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HomeMetabolism6-Phosphogluconate
MoleculeMETABOLITE RECORD

6-Phosphogluconate

The hydrolyzed lactone intermediate oxidized to ribulose 5-phosphate.

6-carbon moleculePentose phosphate pathwayHomo sapiens
REFERENCE IDENTIFIER record
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Learn about 6-Phosphogluconate

6-Phosphogluconate is a small molecule that cells make, use, or change in connected metabolic reactions.

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Record type: molecule. The hydrolyzed lactone intermediate oxidized to ribulose 5-phosphate.
QUICK FACTS

At a glance

Carbon backbone 6 CThis carbon count is shown where it is defined for the molecule.

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Connected records

3 links
Used and produced inPentose phosphate pathwayHandled by6-PhosphogluconolactonaseHandled by6-Phosphogluconate dehydrogenase
STRUCTURED REACTIONS

Where it appears

Open metabolism map
2

Hydrolysis of the lactone

6-Phosphogluconolactonase opens the lactone ring to form 6-phosphogluconate.

Pentose phosphate pathway · irreversible
3

Oxidative decarboxylation

6-Phosphogluconate dehydrogenase releases CO2 and makes a second NADPH.

Pentose phosphate pathway · irreversible