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HomeMetabolismCitrulline
MoleculeMETABOLITE RECORD

Citrulline

A urea-cycle intermediate exported from the mitochondrial matrix to the cytosol.

6-carbon moleculeUrea cycleHomo sapiens
REFERENCE IDENTIFIERCHEBI:18211ChEBI record
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Learn about Citrulline

Citrulline is a small molecule that cells make, use, or change in connected metabolic reactions.

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Record type: molecule. A urea-cycle intermediate exported from the mitochondrial matrix to the cytosol.
QUICK FACTS

At a glance

Carbon backbone 6 CThis carbon count is shown where it is defined for the molecule.

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Connected records

3 links
Used and produced inUrea cycleHandled byOrnithine transcarbamylaseHandled byArgininosuccinate synthase
STRUCTURED REACTIONS

Where it appears

Open metabolism map
2

Citrulline formation

Ornithine transcarbamylase transfers the carbamoyl group to ornithine.

Urea cycle · irreversible
3

Argininosuccinate formation

Argininosuccinate synthase joins citrulline to aspartate, using ATP to AMP.

Urea cycle · irreversible