Conversion of oxaloacetate to phosphoenolpyruvate
PEP carboxykinase uses GTP to decarboxylate and phosphorylate oxaloacetate.
Gluconeogenesis · irreversibleGuanosine triphosphate formed by substrate-level phosphorylation in the citric acid cycle.
GTP is a small molecule that cells make, use, or change in connected metabolic reactions.
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PEP carboxykinase uses GTP to decarboxylate and phosphorylate oxaloacetate.
Gluconeogenesis · irreversibleSuccinyl-CoA synthetase couples thioester cleavage to GTP formation.
Citric acid cycle · irreversibleThe AMP branch uses aspartate and GTP to make AMP and fumarate.
Purine nucleotide synthesis · irreversible