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MoleculeMETABOLITE RECORD

Malate

A four-carbon citric acid cycle intermediate that is oxidized to oxaloacetate.

4-carbon moleculeCitric acid cycleHomo sapiens
REFERENCE IDENTIFIERCHEBI:15589ChEBI record
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Learn about Malate

Malate is a small molecule that cells make, use, or change in connected metabolic reactions.

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Record type: molecule. A four-carbon citric acid cycle intermediate that is oxidized to oxaloacetate.
QUICK FACTS

At a glance

Carbon backbone 4 CThis carbon count is shown where it is defined for the molecule.

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Connected records

3 links
Used and produced inCitric acid cycleHandled byFumaraseHandled byMitochondrial malate dehydrogenase
STRUCTURED REACTIONS

Where it appears

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7

Fumarate hydration

Fumarase adds water across the double bond of fumarate to form malate.

Citric acid cycle · reversible
8

Oxaloacetate regeneration

Malate dehydrogenase oxidizes malate to oxaloacetate and NADH.

Citric acid cycle · irreversible