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HomeMetabolismSuccinyl-CoA
MoleculeMETABOLITE RECORD

Succinyl-CoA

A four-carbon, high-energy thioester intermediate of the citric acid cycle.

4-carbon moleculeCitric acid cycleHomo sapiens
REFERENCE IDENTIFIERCHEBI:15380ChEBI record
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Learn about Succinyl-CoA

Succinyl-CoA is a small molecule that cells make, use, or change in connected metabolic reactions.

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Record type: molecule. A four-carbon, high-energy thioester intermediate of the citric acid cycle.
QUICK FACTS

At a glance

Carbon backbone 4 CThis carbon count is shown where it is defined for the molecule.

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Connected records

5 links
Used and produced inCitric acid cycleProduced inBranched-chain amino acid catabolismHandled by2-Oxoglutarate dehydrogenase complexHandled bySuccinyl-CoA synthetaseHandled byMethylmalonyl-CoA mutase
STRUCTURED REACTIONS

Where it appears

Open metabolism map
4

Second oxidative decarboxylation

The 2-oxoglutarate dehydrogenase complex forms succinyl-CoA, CO2, and NADH.

Citric acid cycle · irreversible
5

GTP formation

Succinyl-CoA synthetase couples thioester cleavage to GTP formation.

Citric acid cycle · irreversible