First one-carbon transfer
GAR transformylase transfers a formyl group from 10-formyl-THF.
Purine nucleotide synthesis · irreversibleThe folate cofactor left after a one-carbon transfer.
Tetrahydrofolate is a small molecule that cells make, use, or change in connected metabolic reactions.
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GAR transformylase transfers a formyl group from 10-formyl-THF.
Purine nucleotide synthesis · irreversibleA second folate-derived formyl group is added to the purine precursor.
Purine nucleotide synthesis · irreversible