Biomarker

Antinuclear Antibodies (ANA)

Antinuclear antibodies

Autoantibodies that bind nuclear components; common in lupus but also found in some healthy people.

Overview

EXPLORE BY LEVEL

ANA are that mistakenly target the body's own cell nuclei. Many people with lupus have them, but so do some healthy people.

Quick Facts

AT A GLANCE
MeasuresAutoantibodies against components of the cell nucleus
CategoryAutoantibody
Interpretation limitA single autoantibody is not a diagnosis: a positive ANA can occur in healthy people and cannot by itself diagnose lupus or any specific disease.

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Recommended Reading

Trusted references for learning more about Antinuclear Antibodies (ANA).

Research Claims

A single autoantibody is not a diagnosis: a positive ANA can occur in healthy people and cannot by itself diagnose lupus or any specific disease.

ANA prevalence rises with age and in women. Diagnosis of SLE or other autoimmune disease requires clinical features and additional laboratory findings.