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Concept

Potency And efficacy

Potency and efficacy

Two different properties: how much drug is needed for an effect and how large an effect the drug can produce.

Overview

EXPLORE BY LEVEL

Potency is about how much medicine is needed to cause an effect. Efficacy is about how large the effect can be. They are not the same thing.

Quick Facts

AT A GLANCE
Explore nextDrug discovery

Follow the Connections

See how Potency And efficacy links to other biological records.

Open network
ConceptTarget Engagementdistinct fromTechniqueHigh-throughput Screeningmeasured in
All 2 Structured Connections
Target Engagement · ConceptDISTINCT FROM →Potency And efficacy · Concept
Potency And efficacy · ConceptMEASURED IN →High-throughput Screening · Technique

Recommended Reading

Trusted references for learning more about Potency And efficacy.

reviewAn overview of DNA-encoded libraries: A versatile tool for drug discoveryPubMed reviewPhage Display Derived Monoclonal Antibodies: From Bench to BedsidePubMed · PMID 32983137
Research Claims

Apparent potency and efficacy can shift with receptor reserve, assay amplification, kinetics, exposure, and endpoint selection. Values from different assay systems should not be treated as directly interchangeable.