Concept

Drug Selectivity

Drug selectivity

How preferentially a drug affects one target or pathway compared with other biological targets.

Overview

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A selective medicine acts more strongly on its intended target than on other proteins. Selectivity can help limit unwanted effects, though no drug is perfectly selective in every setting.

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Trusted references for learning more about Drug Selectivity.

Research Claims

Selectivity profiling combines biochemical, cellular, and sometimes proteome-wide measurements. Therapeutic windows depend on exposure and target biology, not affinity values alone.