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Ketone Bodies

Ketone bodies

Small molecules made mainly by the liver from acetyl-CoA and used as fuel by several tissues during prolonged fasting.

Overview

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During a longer fast, the liver can turn some fat-derived material into ketone bodies. Other organs can use them for energy; the brain uses more during prolonged fasting.

Quick Facts

AT A GLANCE
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ConceptFed And fasting statesproduced during
All 1 Structured Connections
Ketone Bodies · ConceptPRODUCED DURING →Fed And fasting states · Concept

Recommended Reading

Trusted references for learning more about Ketone Bodies.

reviewPhysiology, FastingNCBI Bookshelf reviewEnergy Metabolism in the LiverHepatology Communications · PMC
Research Claims

Ketone-body production and utilization depend on fasting duration, hormonal state, substrate supply, and tissue-specific enzyme expression. Ketones are fuels and signaling metabolites; their concentration alone does not diagnose a disease state.