Disease

Hepatitis C

Hepatitis C virus infection

Liver infection caused by hepatitis C virus; most infections become chronic, and antiviral treatment cures most people.

WORLD HEALTH ORGANIZATION IDENTIFIERHepatitis CView source record ↗

Overview

EXPLORE BY LEVEL

Hepatitis C is a liver infection spread mostly through blood. An test shows whether a person has ever been infected; another test is needed to see whether the is still there.

Quick Facts

AT A GLANCE
CauseHepatitis C virus
Test sequenceHCV antibody, then HCV RNA to identify current infection

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Recommended Reading

Trusted references for learning more about Hepatitis C.

Research Claims

CDC recommends testing for HCV RNA after a repeatedly reactive antibody result, because antibody reactivity is consistent with current infection, resolved infection, or biologic false positivity. Direct-acting antivirals cure most infections, and prior infection does not protect against reinfection.

A reactive anti-HCV result alone does not establish current infection: it can reflect current infection, past resolved infection, or a false-positive result. HCV RNA testing identifies current infection.