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Protein · enzymePROTEIN · ENZYME RECORD

Hexokinase

Transfers a phosphate from ATP to glucose. Hexokinases 1–3 are inhibited by glucose 6-phosphate. Glucokinase is a lower-affinity isozyme found in liver and pancreatic β-cells.

GlycolysisHomo sapiens
REFERENCE IDENTIFIER2.7.1.1EC record
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Hexokinase is a protein that speeds up a chemical reaction. Cells can adjust when and how strongly many enzymes work.

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Record type: enzyme. Transfers a phosphate from ATP to glucose. Hexokinases 1–3 are inhibited by glucose 6-phosphate. Glucokinase is a lower-affinity isozyme found in liver and pancreatic β-cells.
QUICK FACTS

At a glance

HUMAN GENESHK1Explore gene HK2Explore gene HK3Explore gene GCK · glucokinase, EC 2.7.1.2Explore gene
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Connected records

9 links
Catalyzes a step inGlycolysisUsesGlucoseUsesATPProducesGlucose 6-phosphateProducesADPEncoded byHK1Encoded byHK2Encoded byHK3
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Encoded byGCK
STRUCTURED REACTIONS

Reactions it catalyzes

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1

Phosphorylation of glucose

One ATP is spent to add a phosphate to glucose. The charged phosphate traps glucose inside the cell.

Glycolysis · irreversible