MoleculeMETABOLITE RECORD

Glucose 6-phosphate

Glucose carrying a phosphate on carbon 6. The charged phosphate keeps it inside the cell.

6-carbon moleculeGlycolysisHomo sapiens
REFERENCE IDENTIFIERCHEBI:4170ChEBI record
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Learn about Glucose 6-phosphate

6-phosphate is with a phosphate attached. Cells can send it into several different pathways.

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Record type: molecule. Glucose carrying a phosphate on carbon 6. The charged phosphate keeps it inside the cell.
QUICK FACTS

At a glance

Carbon backbone 6 CThis carbon count is shown where it is defined for the molecule.

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STRUCTURED REACTIONS

Where it appears

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1

Phosphorylation of glucose

One ATP is spent to add a phosphate to glucose. The charged phosphate traps glucose inside the cell.

Glycolysis · irreversible
2

Isomerization to fructose 6-phosphate

The ring is rearranged, turning glucose 6-phosphate into fructose 6-phosphate.

Glycolysis · reversible
5

Isomerization and glucose 6-phosphate formation

The remaining shared upper-glycolysis reactions form glucose 6-phosphate.

Gluconeogenesis · irreversible
1

Oxidation of glucose 6-phosphate

G6PD oxidizes glucose 6-phosphate and reduces NADP+ to NADPH.

Pentose phosphate pathway · irreversible
3

Interconversion with glucose 6-phosphate

Phosphoglucomutase interconverts glucose 1-phosphate and glucose 6-phosphate.

Glycogen metabolism · reversible