Acetyl primer loading
The acetyl primer is loaded onto the acyl carrier protein of fatty acid synthase.
Fatty acid synthesis · irreversibleBUILD UP YOUR UNDERSTANDING
Learn about FASN
FASN is a gene: a stretch of DNA that carries instructions used to make a functional RNA or protein.
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QUICK FACTS
At a glance
This gene contributes to FASNIts enzyme and pathway connections are listed below.
FOLLOW THE BIOLOGY
1 linksConnected records
STRUCTURED REACTIONS
Open metabolism map Enzyme reactions
Malonyl condensation
Decarboxylative condensation adds two carbons from malonyl-CoA.
Fatty acid synthesis · irreversibleReduction, dehydration, and second reduction
FASN reduces the keto group, removes water, and reduces the double bond to yield a saturated chain two carbons longer.
Fatty acid synthesis · irreversiblePalmitate release
FASN thioesterase releases palmitate, its principal product.
Fatty acid synthesis · irreversible