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Genomic feature

Enhancer

Enhancer

A regulatory DNA region that can raise transcription by binding regulatory proteins and communicating with a promoter.

Overview

EXPLORE BY LEVEL

An enhancer is a DNA region that can help a gene be used more strongly. Proteins bind to it, and the DNA can fold so those proteins influence the promoter. Enhancers are not always located before a gene; they can be far away or on either side.

Quick Facts

AT A GLANCE
Key ideaMay act at a distance

Follow the Connections

See how Enhancer links to other biological records.

Open network
Genomic featurePromotercan regulate
All 1 Structured Connections
Enhancer · Genomic featureCAN REGULATE →Promoter · Genomic feature

Recommended Reading

Trusted references for learning more about Enhancer.

textbookFrom DNA to RNAMolecular Biology of the Cell · NCBI Bookshelf guidePromoterNational Human Genome Research Institute
Research Claims

Enhancer assignment and causal function require evidence beyond proximity or chromatin marks. Enhancers can contact promoters over long genomic distances, show cell-state specificity, and participate in complex regulatory domains.