Genomic feature
5′ Untranslated region (5′ UTR)
5′ untranslated region (5′ UTR)
The transcribed portion of an mRNA before its coding sequence; it is present in the mature message but is not part of the main protein-coding region.
Overview
EXPLORE BY LEVELThe 5′ UTR is a section at the front of many mature messenger RNAs. It is not translated into the main protein, but it can affect how the message is used by the cell.
Quick Facts
AT A GLANCEKey ideaBefore the coding sequence in mature mRNA
Follow the Connections
See how 5′ Untranslated region (5′ UTR) links to other biological records.
All 1 Structured Connections
Recommended Reading
Trusted references for learning more about 5′ Untranslated region (5′ UTR).
Research Claims
5′ UTRs vary among transcript isoforms and can contain regulatory structures, upstream open reading frames, and binding sites. Their effect depends on cell state and translation machinery.