Genomic feature

5′ Untranslated region (5′ UTR)

5′ untranslated region (5′ UTR)

The transcribed portion of an mRNA before its coding sequence; it is present in the mature message but is not part of the main protein-coding region.

Overview

EXPLORE BY LEVEL

The 5′ UTR is a section at the front of many mature messenger RNAs. It is not translated into the main protein, but it can affect how the message is used by the cell.

Quick Facts

AT A GLANCE
Key ideaBefore the coding sequence in mature mRNA

Follow the Connections

See how 5′ Untranslated region (5′ UTR) links to other biological records.

Open network
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Recommended Reading

Trusted references for learning more about 5′ Untranslated region (5′ UTR).

Research Claims

5′ UTRs vary among transcript isoforms and can contain regulatory structures, upstream open reading frames, and binding sites. Their effect depends on cell state and translation machinery.