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HomeMetabolism6-Phosphoglucono-1,5-lactone
MoleculeMETABOLITE RECORD

6-Phosphoglucono-1,5-lactone

The first oxidized intermediate of the pentose phosphate pathway.

6-carbon moleculePentose phosphate pathwayHomo sapiens
REFERENCE IDENTIFIER record
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Learn about 6-Phosphoglucono-1,5-lactone

6-Phosphoglucono-1,5-lactone is a small molecule that cells make, use, or change in connected metabolic reactions.

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Record type: molecule. The first oxidized intermediate of the pentose phosphate pathway.
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At a glance

Carbon backbone 6 CThis carbon count is shown where it is defined for the molecule.

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Connected records

3 links
Used and produced inPentose phosphate pathwayHandled byGlucose-6-phosphate dehydrogenaseHandled by6-Phosphogluconolactonase
STRUCTURED REACTIONS

Where it appears

Open metabolism map
1

Oxidation of glucose 6-phosphate

G6PD oxidizes glucose 6-phosphate and reduces NADP+ to NADPH.

Pentose phosphate pathway · irreversible
2

Hydrolysis of the lactone

6-Phosphogluconolactonase opens the lactone ring to form 6-phosphogluconate.

Pentose phosphate pathway · irreversible