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HomeMetabolismGlucose-6-phosphate dehydrogenase
Protein · enzymePROTEIN · ENZYME RECORD

Glucose-6-phosphate dehydrogenase

Catalyzes the first, rate-controlling oxidation of the pentose phosphate pathway.

Pentose phosphate pathwayHomo sapiens
REFERENCE IDENTIFIER1.1.1.49EC record
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-6-phosphate dehydrogenase is a protein that speeds up a chemical reaction. Cells can adjust when and how strongly many enzymes work.

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Record type: enzyme. Catalyzes the first, rate-controlling oxidation of the pentose phosphate pathway.
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HUMAN GENESG6PDExplore gene
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Connected records

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Catalyzes a step inPentose phosphate pathwayUsesGlucose 6-phosphateUsesNADP+Produces6-Phosphoglucono-1,5-lactoneProducesNADPHEncoded byG6PD
STRUCTURED REACTIONS

Reactions it catalyzes

Open metabolism map
1

Oxidation of glucose 6-phosphate

G6PD oxidizes glucose 6-phosphate and reduces NADP+ to NADPH.

Pentose phosphate pathway · irreversible