Argininosuccinate formation
Argininosuccinate synthase joins citrulline to aspartate, using ATP to AMP.
Urea cycle · irreversibleAn amino acid that contributes the second nitrogen atom of urea.
Aspartate is a small molecule that cells make, use, or change in connected metabolic reactions.
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Carbon backbone 4 CThis carbon count is shown where it is defined for the molecule.
Argininosuccinate synthase joins citrulline to aspartate, using ATP to AMP.
Urea cycle · irreversibleSAICAR synthetase adds aspartate to CAIR using ATP.
Purine nucleotide synthesis · irreversibleThe AMP branch uses aspartate and GTP to make AMP and fumarate.
Purine nucleotide synthesis · irreversibleCAD adds aspartate and closes the ring to form dihydroorotate.
Pyrimidine nucleotide synthesis · irreversible