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MoleculeMETABOLITE RECORD

Citrate

A six-carbon citric acid cycle intermediate formed from acetyl-CoA and oxaloacetate.

6-carbon moleculeCitric acid cycleHomo sapiens
REFERENCE IDENTIFIERCHEBI:16947ChEBI record
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Learn about Citrate

Citrate is a citric acid cycle molecule and a signal that can also provide carbon for building fats.

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Record type: molecule. A six-carbon citric acid cycle intermediate formed from acetyl-CoA and oxaloacetate.
QUICK FACTS

At a glance

Carbon backbone 6 CThis carbon count is shown where it is defined for the molecule.

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Connected records

5 links
Used and produced inCitric acid cycleUsed inFatty acid synthesisHandled byCitrate synthaseHandled byAconitase 2Handled byATP-citrate lyase
STRUCTURED REACTIONS

Where it appears

Open metabolism map
1

Citrate formation

Citrate synthase condenses acetyl-CoA and oxaloacetate.

Citric acid cycle · irreversible
2

Citrate isomerization

Aconitase rearranges citrate through cis-aconitate to isocitrate.

Citric acid cycle · reversible
1

Cytosolic acetyl-CoA supply

ATP-citrate lyase provides cytosolic acetyl-CoA from exported citrate.

Fatty acid synthesis · irreversible