Aspartate addition and ring closure
CAD adds aspartate and closes the ring to form dihydroorotate.
Pyrimidine nucleotide synthesis · irreversibleA cyclic intermediate oxidized to orotate in the mitochondrial inner membrane.
Dihydroorotate is a small molecule that cells make, use, or change in connected metabolic reactions.
Start here for the main idea. Choose Learn for reactions and connections.
Carbon backbone 5 CThis carbon count is shown where it is defined for the molecule.
CAD adds aspartate and closes the ring to form dihydroorotate.
Pyrimidine nucleotide synthesis · irreversibleDihydroorotate dehydrogenase oxidizes dihydroorotate to orotate and reduces ubiquinone.
Pyrimidine nucleotide synthesis · irreversible