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HomeMetabolism3-Hydroxy-3-methylglutaryl-CoA
MoleculeMETABOLITE RECORD

3-Hydroxy-3-methylglutaryl-CoA

An intermediate formed from acetyl-CoA in the mevalonate pathway.

6-carbon moleculeCholesterol biosynthesisHomo sapiens
REFERENCE IDENTIFIER record
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Learn about 3-Hydroxy-3-methylglutaryl-CoA

3-Hydroxy-3-methylglutaryl-CoA is a small molecule that cells make, use, or change in connected metabolic reactions.

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Record type: molecule. An intermediate formed from acetyl-CoA in the mevalonate pathway.
QUICK FACTS

At a glance

Carbon backbone 6 CThis carbon count is shown where it is defined for the molecule.

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Connected records

3 links
Used and produced inCholesterol biosynthesisHandled byHMG-CoA synthase (cytosolic)Handled byHMG-CoA reductase
STRUCTURED REACTIONS

Where it appears

Open metabolism map
2

HMG-CoA formation

Cytosolic HMG-CoA synthase adds a third acetyl unit to acetoacetyl-CoA.

Cholesterol biosynthesis · irreversible