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HomeMetabolismHMG-CoA synthase (cytosolic)
Protein · enzymePROTEIN · ENZYME RECORD

HMG-CoA synthase (cytosolic)

Condenses acetyl-CoA and acetoacetyl-CoA in the mevalonate pathway.

Cholesterol biosynthesisHomo sapiens
REFERENCE IDENTIFIER2.3.3.10EC record
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Learn about HMG-CoA synthase (cytosolic)

HMG-CoA synthase (cytosolic) is a protein that speeds up a chemical reaction. Cells can adjust when and how strongly many enzymes work.

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Record type: enzyme. Condenses acetyl-CoA and acetoacetyl-CoA in the mevalonate pathway.
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At a glance

HUMAN GENESHMGCS1Explore gene
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Connected records

7 links
Catalyzes a step inCholesterol biosynthesisUsesAcetoacetyl-CoAUsesAcetyl-CoAUsesWaterProduces3-Hydroxy-3-methylglutaryl-CoAProducesCoenzyme AEncoded byHMGCS1
STRUCTURED REACTIONS

Reactions it catalyzes

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2

HMG-CoA formation

Cytosolic HMG-CoA synthase adds a third acetyl unit to acetoacetyl-CoA.

Cholesterol biosynthesis · irreversible