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MoleculeMETABOLITE RECORD

Isocitrate

The rearranged six-carbon isomer of citrate.

6-carbon moleculeCitric acid cycleHomo sapiens
REFERENCE IDENTIFIERCHEBI:16505ChEBI record
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Learn about Isocitrate

Isocitrate is a small molecule that cells make, use, or change in connected metabolic reactions.

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Record type: molecule. The rearranged six-carbon isomer of citrate.
QUICK FACTS

At a glance

Carbon backbone 6 CThis carbon count is shown where it is defined for the molecule.

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Connected records

3 links
Used and produced inCitric acid cycleHandled byAconitase 2Handled byNAD-dependent isocitrate dehydrogenase
STRUCTURED REACTIONS

Where it appears

Open metabolism map
2

Citrate isomerization

Aconitase rearranges citrate through cis-aconitate to isocitrate.

Citric acid cycle · reversible
3

First oxidative decarboxylation

NAD-dependent isocitrate dehydrogenase produces 2-oxoglutarate, CO2, and NADH.

Citric acid cycle · irreversible