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HomeMetabolismNAD-dependent isocitrate dehydrogenase
Protein · enzymePROTEIN · ENZYME RECORD

NAD-dependent isocitrate dehydrogenase

Oxidatively decarboxylates isocitrate to 2-oxoglutarate.

Citric acid cycleHomo sapiens
REFERENCE IDENTIFIER1.1.1.41EC record
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NAD-dependent isocitrate dehydrogenase is a protein that speeds up a chemical reaction. Cells can adjust when and how strongly many enzymes work.

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Record type: enzyme. Oxidatively decarboxylates isocitrate to 2-oxoglutarate.
QUICK FACTS

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HUMAN GENESIDH3AExplore gene IDH3BExplore gene IDH3GExplore gene
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Connected records

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Catalyzes a step inCitric acid cycleUsesIsocitrateUsesNAD+Produces2-OxoglutarateProducesCarbon dioxideProducesNADHProducesProtonEncoded byIDH3A
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Encoded byIDH3BEncoded byIDH3G
STRUCTURED REACTIONS

Reactions it catalyzes

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3

First oxidative decarboxylation

NAD-dependent isocitrate dehydrogenase produces 2-oxoglutarate, CO2, and NADH.

Citric acid cycle · irreversible