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HomeMetabolism3-Ketoacyl-CoA
MoleculeMETABOLITE RECORD

3-Ketoacyl-CoA

The oxidized intermediate cleaved by thiolase during beta-oxidation.

Fatty acid β-oxidationHomo sapiens
REFERENCE IDENTIFIER record
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3-Ketoacyl-CoA is a small molecule that cells make, use, or change in connected metabolic reactions.

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Record type: molecule. The oxidized intermediate cleaved by thiolase during beta-oxidation.
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Connected records

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Used and produced inFatty acid β-oxidationHandled byMitochondrial trifunctional proteinHandled byAcetyl-CoA acyltransferase 2
STRUCTURED REACTIONS

Where it appears

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4

Second oxidation

The hydroxyacyl intermediate is oxidized to 3-ketoacyl-CoA, producing NADH.

Fatty acid β-oxidation · irreversible
5

Thiolytic cleavage

Thiolase releases one acetyl-CoA and a fatty acyl-CoA shortened by two carbons.

Fatty acid β-oxidation · irreversible