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HomeMetabolismAcetyl-CoA acyltransferase 2
Protein · enzymePROTEIN · ENZYME RECORD

Acetyl-CoA acyltransferase 2

Cleaves 3-ketoacyl-CoA with CoA, releasing acetyl-CoA and a shortened acyl-CoA.

Fatty acid β-oxidationHomo sapiens
REFERENCE IDENTIFIER2.3.1.16EC record
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Learn about Acetyl-CoA acyltransferase 2

Acetyl-CoA acyltransferase 2 is a protein that speeds up a chemical reaction. Cells can adjust when and how strongly many enzymes work.

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Record type: enzyme. Cleaves 3-ketoacyl-CoA with CoA, releasing acetyl-CoA and a shortened acyl-CoA.
QUICK FACTS

At a glance

HUMAN GENESACAA2Explore gene
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Connected records

13 links
Catalyzes a step inFatty acid β-oxidationUses3-Ketoacyl-CoAUsesCoenzyme AProducesAcetyl-CoAProducesShortened fatty acyl-CoACatalyzes a step inCholesterol biosynthesisUsesAcetyl-CoAProducesAcetoacetyl-CoA
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ProducesCoenzyme ACatalyzes a step inBranched-chain amino acid catabolismUsesBranched-chain acyl-CoA intermediatesProducesPropionyl-CoAEncoded byACAA2
STRUCTURED REACTIONS

Reactions it catalyzes

Open metabolism map
5

Thiolytic cleavage

Thiolase releases one acetyl-CoA and a fatty acyl-CoA shortened by two carbons.

Fatty acid β-oxidation · irreversible
1

Acetoacetyl-CoA formation

Thiolase condenses two acetyl-CoA molecules to form acetoacetyl-CoA.

Cholesterol biosynthesis · irreversible