BASEBiological Archive
for Science & Education
Search
HomeMetabolismMalonyl-CoA
MoleculeMETABOLITE RECORD

Malonyl-CoA

The activated two-carbon donor for fatty-acid synthesis; decarboxylation drives chain extension.

3-carbon moleculeFatty acid synthesisHomo sapiens
REFERENCE IDENTIFIER record
BUILD UP YOUR UNDERSTANDING

Learn about Malonyl-CoA

Malonyl-CoA is a small molecule that cells make, use, or change in connected metabolic reactions.

Start here for the main idea. Choose Learn for reactions and connections.

Record type: molecule. The activated two-carbon donor for fatty-acid synthesis; decarboxylation drives chain extension.
QUICK FACTS

At a glance

Carbon backbone 3 CThis carbon count is shown where it is defined for the molecule.

FOLLOW THE BIOLOGY

Connected records

3 links
Used and produced inFatty acid synthesisHandled byAcetyl-CoA carboxylaseHandled byFatty acid synthase
STRUCTURED REACTIONS

Where it appears

Open metabolism map
2

Malonyl-CoA formation

Acetyl-CoA carboxylase uses ATP and biotin to make malonyl-CoA.

Fatty acid synthesis · irreversible
4

Malonyl condensation

Decarboxylative condensation adds two carbons from malonyl-CoA.

Fatty acid synthesis · irreversible