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HomeMetabolism5-Phosphoribosyl 1-pyrophosphate
MoleculeMETABOLITE RECORD

5-Phosphoribosyl 1-pyrophosphate

An activated ribose phosphate used to assemble purine nucleotides and to enter pyrimidine synthesis.

5-carbon moleculePurine nucleotide synthesisHomo sapiens
REFERENCE IDENTIFIERCHEBI:17111ChEBI record
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Learn about 5-Phosphoribosyl 1-pyrophosphate

5-Phosphoribosyl 1-pyrophosphate is a small molecule that cells make, use, or change in connected metabolic reactions.

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Record type: molecule. An activated ribose phosphate used to assemble purine nucleotides and to enter pyrimidine synthesis.
QUICK FACTS

At a glance

Carbon backbone 5 CThis carbon count is shown where it is defined for the molecule.

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Connected records

5 links
Used and produced inPurine nucleotide synthesisUsed inPyrimidine nucleotide synthesisHandled byRibose-phosphate pyrophosphokinaseHandled byGlutamine phosphoribosylpyrophosphate amidotransferaseHandled byOrotate phosphoribosyltransferase
STRUCTURED REACTIONS

Where it appears

Open metabolism map
2

Committed purine nitrogen addition

Glutamine-PRPP amidotransferase commits PRPP to de novo purine synthesis.

Purine nucleotide synthesis · irreversible