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HomeMetabolismGlutamine phosphoribosylpyrophosphate amidotransferase
Protein · enzymePROTEIN · ENZYME RECORD

Glutamine phosphoribosylpyrophosphate amidotransferase

Catalyzes the first committed step of de novo purine synthesis.

Purine nucleotide synthesisHomo sapiens
REFERENCE IDENTIFIER2.4.2.14EC record
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Learn about Glutamine phosphoribosylpyrophosphate amidotransferase

Glutamine phosphoribosylpyrophosphate amidotransferase is a protein that speeds up a chemical reaction. Cells can adjust when and how strongly many enzymes work.

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Record type: enzyme. Catalyzes the first committed step of de novo purine synthesis.
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At a glance

HUMAN GENESPPATExplore gene
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Connected records

7 links
Catalyzes a step inPurine nucleotide synthesisUses5-Phosphoribosyl 1-pyrophosphateUsesGlutamineProduces5-PhosphoribosylamineProducesGlutamateProducesPyrophosphateEncoded byPPAT
STRUCTURED REACTIONS

Reactions it catalyzes

Open metabolism map
2

Committed purine nitrogen addition

Glutamine-PRPP amidotransferase commits PRPP to de novo purine synthesis.

Purine nucleotide synthesis · irreversible