Activation to UDP-glucose
UDP-glucose pyrophosphorylase activates glucose 1-phosphate with UTP.
Glycogen metabolism · irreversibleBUILD UP YOUR UNDERSTANDING
Learn about Pyrophosphate
Pyrophosphate is a small molecule that cells make, use, or change in connected metabolic reactions.
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QUICK FACTS
At a glance
FOLLOW THE BIOLOGY
10 linksConnected records
Produced inGlycogen metabolismProduced inUrea cycleProduced inPurine nucleotide synthesisProduced inPyrimidine nucleotide synthesisHandled byUDP-glucose pyrophosphorylaseHandled byArgininosuccinate synthaseHandled byRibose-phosphate pyrophosphokinaseHandled byGlutamine phosphoribosylpyrophosphate amidotransferase
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STRUCTURED REACTIONS
Open metabolism map Where it appears
Argininosuccinate formation
Argininosuccinate synthase joins citrulline to aspartate, using ATP to AMP.
Urea cycle · irreversiblePRPP formation
PRPP synthetase activates ribose 5-phosphate using ATP.
Purine nucleotide synthesis · irreversibleCommitted purine nitrogen addition
Glutamine-PRPP amidotransferase commits PRPP to de novo purine synthesis.
Purine nucleotide synthesis · irreversibleGMP branch
The GMP branch oxidizes IMP to XMP and adds nitrogen from glutamine using ATP.
Purine nucleotide synthesis · irreversibleOMP formation
Orotate phosphoribosyltransferase transfers activated ribose phosphate from PRPP to orotate.
Pyrimidine nucleotide synthesis · irreversible