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Apoptosis Signaling

Apoptosis signaling

The regulated pathways cells use to initiate and execute programmed cell death.

Overview

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When a cell cannot safely continue, signals can start an orderly self-removal process called apoptosis.

Quick Facts

AT A GLANCE
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See how Apoptosis Signaling links to other biological records.

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ProcessCell Cyclecrosstalks with
All 1 Structured Connections
Cell Cycle · ProcessCROSSTALKS WITH →Apoptosis Signaling · Pathway

Recommended Reading

Trusted references for learning more about Apoptosis Signaling.

pathwayApoptosis (R-HSA-109581)Reactome · Homo sapiens databaseTP53 tumor protein p53 (Gene ID 7157)NCBI Gene reviewUnravelling mechanisms of p53-mediated tumour suppressionNature Reviews Cancer · PMID 24739573
Research Claims

Apoptosis is a regulated network with mitochondrial, death-receptor, and caspase-control modules. p53 can influence some intrinsic responses but is not required for every apoptotic event.