BASEBiological Archive
for Science & Education
Search
HomeExploreProtein Kinases
Concept

Protein Kinases

Protein kinases

Enzymes that transfer phosphate groups, usually from ATP, onto protein targets.

Overview

EXPLORE BY LEVEL

A protein kinase is an that can add a phosphate tag to another protein. That tag can change the target's activity, location, or partners.

Quick Facts

AT A GLANCE
Explore nextCell signaling

Follow the Connections

See how Protein Kinases links to other biological records.

Open network
ProcessProtein Phosphorylationadds phosphate inConceptHow Kinase inhibitors worktargets
All 2 Structured Connections
Protein Kinases · ConceptADDS PHOSPHATE IN →Protein Phosphorylation · Process
How Kinase inhibitors work · ConceptTARGETS →Protein Kinases · Concept

Recommended Reading

Trusted references for learning more about Protein Kinases.

textbookGeneral Principles of Cell CommunicationMolecular Biology of the Cell · NCBI Bookshelf textbookThe Cell Cycle and Programmed Cell DeathMolecular Biology of the Cell · NCBI Bookshelf reviewMechanisms of drug resistance in kinasesPubMed · PMID 21235428
Research Claims

Kinase signaling uses dynamic, site-specific phosphorylation networks. A phosphorylation event is not inherently activating; its effect depends on the protein, residue, and cellular context.