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Protein · enzymePROTEIN · ENZYME RECORD

Enolase

Mg2+-dependent dehydration of 2-phosphoglycerate to phosphoenolpyruvate.

GlycolysisHomo sapiens
REFERENCE IDENTIFIER4.2.1.11EC record
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Record type: enzyme. Mg2+-dependent dehydration of 2-phosphoglycerate to phosphoenolpyruvate.
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HUMAN GENESENO1Explore gene ENO2Explore gene ENO3Explore gene
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Connected records

11 links
Catalyzes a step inGlycolysisUses2-PhosphoglycerateProducesPhosphoenolpyruvateProducesWaterCatalyzes a step inGluconeogenesisUsesPhosphoenolpyruvateUsesWaterProduces2-Phosphoglycerate
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Encoded byENO1Encoded byENO2Encoded byENO3
STRUCTURED REACTIONS

Reactions it catalyzes

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9

Dehydration to phosphoenolpyruvate

Removing a water molecule forms phosphoenolpyruvate, whose phosphate has very high transfer potential.

Glycolysis · reversible
3

Reverse the glycolytic payoff sequence

The reversible lower-glycolysis reactions proceed from PEP toward glyceraldehyde 3-phosphate.

Gluconeogenesis · reversible