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HomeMetabolismGlucose-6-phosphate isomerase
Protein · enzymePROTEIN · ENZYME RECORD

Glucose-6-phosphate isomerase

Interconverts glucose 6-phosphate and fructose 6-phosphate.

GlycolysisHomo sapiens
REFERENCE IDENTIFIER5.3.1.9EC record
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Learn about Glucose-6-phosphate isomerase

-6-phosphate isomerase is a protein that speeds up a chemical reaction. Cells can adjust when and how strongly many enzymes work.

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Record type: enzyme. Interconverts glucose 6-phosphate and fructose 6-phosphate.
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At a glance

HUMAN GENESGPIExplore gene
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Connected records

7 links
Catalyzes a step inGlycolysisUsesGlucose 6-phosphateProducesFructose 6-phosphateCatalyzes a step inGluconeogenesisUsesFructose 6-phosphateProducesGlucose 6-phosphateEncoded byGPI
STRUCTURED REACTIONS

Reactions it catalyzes

Open metabolism map
2

Isomerization to fructose 6-phosphate

The ring is rearranged, turning glucose 6-phosphate into fructose 6-phosphate.

Glycolysis · reversible
5

Isomerization and glucose 6-phosphate formation

The remaining shared upper-glycolysis reactions form glucose 6-phosphate.

Gluconeogenesis · irreversible