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Gene

MDM2

MDM2 proto-oncogene

A gene whose protein product is a major negative regulator of p53 stability.

NCBI GENE IDENTIFIER4193View source record ↗

Overview

EXPLORE BY LEVEL

MDM2 helps keep p53 levels under control. When this control changes, a cell's response to stress can change too.

Quick Facts

AT A GLANCE
Gene ID4193
OrganismHomo sapiens
Rolep53 regulation

Follow the Connections

See how MDM2 links to other biological records.

Open network
Proteinp53regulates
All 1 Structured Connections
MDM2 · GeneREGULATES →p53 · Protein

Recommended Reading

Trusted references for learning more about MDM2.

databaseMDM2 proto-oncogene (Gene ID 4193)NCBI Gene pathwayStabilization of p53 (R-HSA-69541)Reactome
Research Claims

MDM2 is part of the regulatory network controlling p53 stability.