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Genomic feature

Coding Sequence (CDS)

Coding sequence (CDS)

The part of a transcript annotated as specifying a protein sequence, from its translation start through its termination codon.

Overview

EXPLORE BY LEVEL

The coding sequence is the part of an RNA message that the ribosome translates into a chain of amino acids. It is only one part of many genes: control regions and untranslated regions also matter.

Quick Facts

AT A GLANCE
Key ideaTranslated into a polypeptide

Follow the Connections

See how Coding Sequence (CDS) links to other biological records.

Open network
ProcessTranslationtranslated during
All 1 Structured Connections
Coding Sequence (CDS) · Genomic featureTRANSLATED DURING →Translation · Process

Recommended Reading

Trusted references for learning more about Coding Sequence (CDS).

textbookFrom RNA to proteinMolecular Biology of the Cell · NCBI Bookshelf guideOpen Reading FrameNational Human Genome Research Institute
Research Claims

CDS boundaries depend on transcript isoform and annotation conventions. Alternative initiation, termination, frameshifting, and recoding can complicate a simple one-CDS/one-protein model.