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Molecule

Histidine

L-histidine

Histidine is an amino acid with an imidazole ring that can gain or lose a proton near biologically relevant pH.

Overview

EXPLORE BY LEVEL

Histidine is an with an imidazole ring that can gain or lose a proton near biologically relevant pH.

Quick Facts

AT A GLANCE
One-letter codeH
Three-letter codeHis
Chemical formulaC₆H₉N₃O₂
Side chainImidazole ring
Show 3 more facts
Side-chain chemistryPolar; ionizable basic side chain
Human dietary contextEssential in the human diet
Protein-building setOne of the 20 standard protein-building amino acids

Follow the Connections

See how Histidine links to other biological records.

Open network
ConceptAmino AcidsincludesProcessTranslationincorporated during
All 2 Structured Connections
Amino Acids · ConceptINCLUDES →Histidine · Molecule
Histidine · MoleculeINCORPORATED DURING →Translation · Process

Recommended Reading

Trusted references for learning more about Histidine.

textbookChemical Components of a CellMolecular Biology of the Cell · NCBI Bookshelf textbookFrom RNA to proteinMolecular Biology of the Cell · NCBI Bookshelf textbookBiochemistry · Essential Amino AcidsNCBI Bookshelf · StatPearls
Research Claims

Histidine is a standard amino acid commonly used to build proteins.

Histidine uses the residue codes His and H.

Histidine is classified as essential in the usual human diet.