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Cholesterol Homeostasis

Cholesterol homeostasis

The balance of cholesterol synthesis, uptake, transport, and removal across tissues.

Overview

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The body makes cholesterol and also gets it from food. Cells and organs balance how much they make, take up, and move around.

Quick Facts

AT A GLANCE
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Follow the Connections

See how Cholesterol Homeostasis links to other biological records.

Open network
ProteinHMG-CoA Reductaseregulated by
All 1 Structured Connections
Cholesterol Homeostasis · ProcessREGULATED BY →HMG-CoA Reductase · Protein

Recommended Reading

Trusted references for learning more about Cholesterol Homeostasis.

pathwayCholesterol biosynthesis (R-HSA-191273)Reactome · Homo sapiens articleEvolocumab and Clinical Outcomes in Patients with Cardiovascular DiseasePubMed · PMID 28304224 articleInclisiran in Patients at High Cardiovascular Risk with Elevated LDL CholesterolPubMed · PMID 28306389
Research Claims

Systemic cholesterol homeostasis is distributed across liver, intestine, peripheral tissues, and circulating lipoproteins. Biomarker changes and clinical outcomes should be distinguished.