Process
Exon Skipping
Exon skipping
A splicing strategy that omits a selected exon from pre-mRNA, sometimes restoring the reading frame of a disease-associated transcript.
Overview
EXPLORE BY LEVELSome genetic diseases disrupt how a gene's message is assembled. An antisense strand can hide one exon during editing, allowing the cell to join other sections and sometimes make a shorter working protein.
Quick Facts
AT A GLANCEExplore nextRNA therapeutics
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See how Exon Skipping links to other biological records.
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Recommended Reading
Trusted references for learning more about Exon Skipping.
Research Claims
Exon-skipping outcomes depend on variant position, reading-frame restoration, transcript abundance, tissue delivery, and residual protein function. A molecular effect does not alone establish meaningful clinical benefit.