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Signal Amplification

Signal amplification

A signaling process in which one activated component influences many downstream molecules.

Overview

EXPLORE BY LEVEL

One activated protein can switch on many copies of the next component. Repeating this can make a small outside signal produce a larger inside response.

Quick Facts

AT A GLANCE
Explore nextCell signaling

Follow the Connections

See how Signal Amplification links to other biological records.

Open network
ConceptCell Signalingcan amplify throughPathwayRAS-RAF-MEK-ERK Signaling (MAPK)occurs in
All 2 Structured Connections
Cell Signaling · ConceptCAN AMPLIFY THROUGH →Signal Amplification · Process
Signal Amplification · ProcessOCCURS IN →RAS-RAF-MEK-ERK Signaling (MAPK) · Pathway

Recommended Reading

Trusted references for learning more about Signal Amplification.

textbookGeneral Principles of Cell CommunicationMolecular Biology of the Cell · NCBI Bookshelf pathwayRAF/MAP kinase cascade (R-HSA-5673001)Reactome · Homo sapiens
Research Claims

The gain of a signaling network depends on kinetics, stoichiometry, localization, feedback, and adaptation. Amplification is not necessarily unlimited or proportional across all signal strengths.