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Protein

AGO2

argonaute RISC catalytic component 2

The catalytic Argonaute component of many siRNA-loaded RISC complexes. Cleavage depends on guide-target pairing, RNA accessibility, and the relevant cellular context.

Overview

EXPLORE BY LEVEL

AGO2 is a protein that helps pass or control signals inside cells. The catalytic Argonaute component of many siRNA-loaded RISC complexes. Cleavage depends on guide-target pairing, RNA accessibility, and the relevant cellular context.

Quick Facts

AT A GLANCE
Encoded byAGO2
Rolerna interference; risc

Follow the Connections

See how AGO2 links to other biological records.

Open network
Molecular complexRNA-induced Silencing complexcontains catalytic componentGeneAGO2encodesProcessRNA Interferenceparticipates in
All 4 Structured Connections
RNA-induced Silencing complex · Molecular complexCONTAINS CATALYTIC COMPONENT →AGO2 · Protein
AGO2 · GeneENCODES →AGO2 · Protein
AGO2 · ProteinPARTICIPATES IN →RNA Interference · Process
AGO2 · ProteinPARTICIPATES IN →RNA-induced Silencing complex · Molecular complex

Recommended Reading

Trusted references for learning more about AGO2.

databaseAGO2 (27161)NCBI Gene articleRNA cleavage products generated by antisense oligonucleotides and siRNAs are processed by the RNA surveillance machineryNucleic Acids Research · PMID 26843429
Research Claims

The catalytic Argonaute component of many siRNA-loaded RISC complexes. Cleavage depends on guide-target pairing, RNA accessibility, and the relevant cellular context.