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Protein

Insulin Receptor

Insulin receptor

A cell-surface receptor that detects insulin and initiates intracellular signaling.

Overview

EXPLORE BY LEVEL

The insulin sits in the cell membrane. When insulin binds, the starts a chain of messages inside the cell.

Quick Facts

AT A GLANCE
Explore nextCell signaling

Follow the Connections

See how Insulin Receptor links to other biological records.

Open network
ProteinInsulinbindsPathwayInsulin SignalingactivatesConceptLigands And receptorsbinds
All 3 Structured Connections
Insulin · ProteinBINDS →Insulin Receptor · Protein
Insulin Receptor · ProteinACTIVATES →Insulin Signaling · Pathway
Ligands And receptors · ConceptBINDS →Insulin Receptor · Protein

Recommended Reading

Trusted references for learning more about Insulin Receptor.

pathwayInsulin binds the insulin receptor (R-HSA-74716)Reactome · Homo sapiens pathwaySignaling by insulin receptor (R-HSA-74752)Reactome · Homo sapiens
Research Claims

Insulin receptor output is regulated by ligand occupancy, autophosphorylation, substrate recruitment, endocytosis, and dephosphorylation.