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Protein

p110α (PIK3CA)

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

The catalytic subunit of a common class IA PI3K complex. Together with a regulatory subunit, it can phosphorylate PIP2 to form PIP3.

Overview

EXPLORE BY LEVEL

p110α (PIK3CA) is a protein that helps pass or control signals inside cells. The catalytic subunit of a common class IA PI3K complex. Together with a regulatory subunit, it can phosphorylate PIP2 to form PIP3.

Quick Facts

AT A GLANCE
Encoded byPIK3CA
Rolepi3k akt mtor

Follow the Connections

See how p110α (PIK3CA) links to other biological records.

Open network
GenePIK3CAencodesPathwayPI3K-AKT-mTOR Signalingparticipates inMolecular complexClass IA PI3Ksubunit of
All 3 Structured Connections
PIK3CA · GeneENCODES →p110α (PIK3CA) · Protein
p110α (PIK3CA) · ProteinPARTICIPATES IN →PI3K-AKT-mTOR Signaling · Pathway
p110α (PIK3CA) · ProteinSUBUNIT OF →Class IA PI3K · Molecular complex

Recommended Reading

Trusted references for learning more about p110α (PIK3CA).

pathwayPIP3 activates AKT signaling (R-HSA-1257604)Reactome · Homo sapiens databasePIK3CA (5290)NCBI Gene pathwayMTOR signalling (R-HSA-165159)Reactome · Homo sapiens
Research Claims

The catalytic subunit of a common class IA PI3K complex. Together with a regulatory subunit, it can phosphorylate PIP2 to form PIP3.