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Protein

TSC2 (tuberin)

TSC complex subunit 2

A catalytic component of the TSC1–TSC2 complex that promotes conversion of active RHEB-GTP toward RHEB-GDP, reducing mTORC1 activation.

Overview

EXPLORE BY LEVEL

TSC2 (tuberin) is a protein that helps pass or control signals inside cells. A catalytic component of the TSC1–TSC2 complex that promotes conversion of active RHEB-GTP toward RHEB-GDP, reducing mTORC1 activation.

Quick Facts

AT A GLANCE
Encoded byTSC2
Rolepi3k akt mtor

Follow the Connections

See how TSC2 (tuberin) links to other biological records.

Open network
GeneTSC2encodesPathwayPI3K-AKT-mTOR Signalingparticipates inMolecular complexTSC1–TSC2 Complexsubunit of
All 3 Structured Connections
TSC2 · GeneENCODES →TSC2 (tuberin) · Protein
TSC2 (tuberin) · ProteinPARTICIPATES IN →PI3K-AKT-mTOR Signaling · Pathway
TSC2 (tuberin) · ProteinSUBUNIT OF →TSC1–TSC2 Complex · Molecular complex

Recommended Reading

Trusted references for learning more about TSC2 (tuberin).

pathwayMTOR signalling (R-HSA-165159)Reactome · Homo sapiens databaseTSC2 (7249)NCBI Gene
Research Claims

A catalytic component of the TSC1–TSC2 complex that promotes conversion of active RHEB-GTP toward RHEB-GDP, reducing mTORC1 activation.