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HomeMetabolismPyruvate carboxylase
Protein · enzymePROTEIN · ENZYME RECORD

Pyruvate carboxylase

Biotin-dependent mitochondrial enzyme that carboxylates pyruvate to oxaloacetate.

GluconeogenesisHomo sapiens
REFERENCE IDENTIFIER6.4.1.1EC record
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Pyruvate carboxylase is a protein that speeds up a chemical reaction. Cells can adjust when and how strongly many enzymes work.

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Record type: enzyme. Biotin-dependent mitochondrial enzyme that carboxylates pyruvate to oxaloacetate.
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HUMAN GENESPCExplore gene
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Catalyzes a step inGluconeogenesisUsesPyruvateUsesBicarbonateUsesATPProducesOxaloacetateProducesADPProducesInorganic phosphateEncoded byPC
STRUCTURED REACTIONS

Reactions it catalyzes

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Carboxylation of pyruvate

Pyruvate gains a carbon dioxide equivalent to form oxaloacetate, using ATP and biotin.

Gluconeogenesis · irreversible