Protein

Beta-globin

hemoglobin subunit beta

Beta-globin pairs with alpha-globin and heme to form hemoglobin, the oxygen-binding protein in red blood cells.

UNIPROTKB IDENTIFIERP68871View source record ↗

Overview

EXPLORE BY LEVEL

is one of the pieces that make up . sits inside red blood cells and picks up oxygen in the lungs so it can be delivered around the body.

Quick Facts

AT A GLANCE

Encoded byHBB

Length147 amino acids

ComplexAdult hemoglobin A (alpha2-beta2)

CofactorHeme b

Follow the Connections

See how Beta-globin links to other biological records.

GeneHBBencodes Molecular complexAdult Hemoglobin Asubunit of PathwayIntracellular Oxygen transportparticipates in VariantHbS β6 Glu→Val Variantchanges sequence of

All 4 Structured Connections

HBB · GeneENCODES →Beta-globin · Protein

Beta-globin · ProteinSUBUNIT OF →Adult Hemoglobin A · Molecular complex

Beta-globin · ProteinPARTICIPATES IN →Intracellular Oxygen transport · Pathway

HbS β6 Glu→Val Variant · VariantCHANGES SEQUENCE OF →Beta-globin · Protein

Recommended Reading

Trusted references for learning more about Beta-globin.

databaseHemoglobin subunit beta (P68871)UniProtKB databaseHBB geneMedlinePlus Genetics pathwayO2/CO2 exchange in erythrocytes (R-HSA-1480926)Reactome · Homo sapiens databaseAbout sickle cell diseaseCenters for Disease Control and Prevention

Show 3 more sources

HBB hemoglobin subunit beta (Gene ID 3043)NCBI Gene · database Hemoglobin (R-ICO-012815)Reactome · database Intracellular oxygen transport (R-HSA-8981607)Reactome · Homo sapiens · pathway

Research Claims

Human beta-globin is a component of hemoglobin and carries one heme group in the hemoglobin complex.

[1] UniProtKB · [2] MedlinePlus Genetics

Hemoglobin in red blood cells binds oxygen and releases it to tissues.

[1] Reactome · Homo sapiens · [2] Centers for Disease Control and Prevention