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Protein

ERK2 (MAPK1)

mitogen-activated protein kinase 1

A MAP kinase activated by MEK1 or MEK2. ERK2 can phosphorylate many targets and move into the nucleus after some signals.

Overview

EXPLORE BY LEVEL

ERK2 (MAPK1) is a protein that helps pass or control signals inside cells. A MAP kinase activated by MEK1 or MEK2. ERK2 can phosphorylate many targets and move into the nucleus after some signals.

Quick Facts

AT A GLANCE
Encoded byMAPK1
Rolemapk signaling

Follow the Connections

See how ERK2 (MAPK1) links to other biological records.

Open network
GeneMAPK1encodesPathwayRAS-RAF-MEK-ERK Signaling (MAPK)participates inProteinMEK1 (MAP2K1)phosphorylatesProteinMEK2 (MAP2K2)phosphorylates
All 5 Structured Connections
MAPK1 · GeneENCODES →ERK2 (MAPK1) · Protein
ERK2 (MAPK1) · ProteinPARTICIPATES IN →RAS-RAF-MEK-ERK Signaling (MAPK) · Pathway
MEK1 (MAP2K1) · ProteinPHOSPHORYLATES →ERK2 (MAPK1) · Protein
MEK2 (MAP2K2) · ProteinPHOSPHORYLATES →ERK2 (MAPK1) · Protein
DUSP6 · ProteinDEPHOSPHORYLATES →ERK2 (MAPK1) · Protein

Recommended Reading

Trusted references for learning more about ERK2 (MAPK1).

pathwayRAF/MAP kinase cascade (R-HSA-5673001)Reactome · Homo sapiens databaseMAPK1 (5594)NCBI Gene
Research Claims

A MAP kinase activated by MEK1 or MEK2. ERK2 can phosphorylate many targets and move into the nucleus after some signals.