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Protein

PDK1 (PDPK1)

3-phosphoinositide dependent protein kinase 1

A kinase recruited in phosphoinositide signaling that phosphorylates AKT at threonine 308. This is distinct from pyruvate dehydrogenase kinases, which are also abbreviated PDKs.

Overview

EXPLORE BY LEVEL

PDK1 (PDPK1) is a protein that helps pass or control signals inside cells. A kinase recruited in phosphoinositide signaling that phosphorylates AKT at threonine 308. This is distinct from pyruvate dehydrogenase kinases, which are also abbreviated PDKs.

Quick Facts

AT A GLANCE
Encoded byPDPK1
Rolepi3k akt mtor

Follow the Connections

See how PDK1 (PDPK1) links to other biological records.

Open network
GenePDPK1encodesPathwayPI3K-AKT-mTOR Signalingparticipates inMoleculePIP3recruitsProteinAKT1phosphorylates
All 4 Structured Connections
PDPK1 · GeneENCODES →PDK1 (PDPK1) · Protein
PDK1 (PDPK1) · ProteinPARTICIPATES IN →PI3K-AKT-mTOR Signaling · Pathway
PIP3 · MoleculeRECRUITS →PDK1 (PDPK1) · Protein
PDK1 (PDPK1) · ProteinPHOSPHORYLATES →AKT1 · Protein

Recommended Reading

Trusted references for learning more about PDK1 (PDPK1).

pathwayPIP3 activates AKT signaling (R-HSA-1257604)Reactome · Homo sapiens databasePDPK1 (5170)NCBI Gene
Research Claims

A kinase recruited in phosphoinositide signaling that phosphorylates AKT at threonine 308. This is distinct from pyruvate dehydrogenase kinases, which are also abbreviated PDKs.