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Protein

RHEB

Ras homolog, mTORC1 binding

A small GTPase that can activate mTORC1 when GTP-bound. The TSC complex regulates the balance between RHEB nucleotide states.

Overview

EXPLORE BY LEVEL

RHEB is a protein that helps pass or control signals inside cells. A small GTPase that can activate mTORC1 when GTP-bound. The TSC complex regulates the balance between RHEB nucleotide states.

Quick Facts

AT A GLANCE
Encoded byRHEB
Rolepi3k akt mtor

Follow the Connections

See how RHEB links to other biological records.

Open network
GeneRHEBencodesPathwayPI3K-AKT-mTOR Signalingparticipates inMolecular complexTSC1–TSC2 ComplexinactivatesMolecular complexmTORC1activates
All 4 Structured Connections
RHEB · GeneENCODES →RHEB · Protein
RHEB · ProteinPARTICIPATES IN →PI3K-AKT-mTOR Signaling · Pathway
TSC1–TSC2 Complex · Molecular complexINACTIVATES →RHEB · Protein
RHEB · ProteinACTIVATES →mTORC1 · Molecular complex

Recommended Reading

Trusted references for learning more about RHEB.

pathwayMTOR signalling (R-HSA-165159)Reactome · Homo sapiens databaseRHEB (6009)NCBI Gene
Research Claims

A small GTPase that can activate mTORC1 when GTP-bound. The TSC complex regulates the balance between RHEB nucleotide states.